Possible, sure; a good idea...wellll, that largely depends on how concerned you are about EE viability. DC-based casting gets pretty rough in EEs, esp. if you don't have the past lives, gear, etc. to make up for any splashing. There's also less synergy between divine casters and rogue / arty splashes than there is with wizard.
One of my just-for-fun builds is a DEX-based rog 5 / druid 15 - either TWF w/daggers or Acrobat staff build. Its melee DPS pales compared to pure rogues, ofc; but the druid levels provide plenty of healing, buffs, and utility spells like Sleet Storm. It's not a serious caster DPS build, either, but it can use Ice Storm and both Creeping Colds, due to those spells having no DCs. Alternatively, she can go for fire elemental form and use Body of the Sun; DCs stink, but it's a Fort save so you always do at least half-dmg.
I posted a
repeater bard a while ago; it would not be hard to convert it to any caster class, though the lack of metamagics sucks.
