Do you have the Falconry tree? If so, you can play a WIS-based melee / healer cleric like
Axel's build. Note that the
recent HP changes got rid of Epic Defensive Fighting while sprinkling more HP bonuses elsewhere, such as the combat-style feats and tier-5 Warpriest.
Usually the heavily-multiclassed builds are based on adding Enhancements from specific tree(s) E.g. paladin 5 / cleric 15 trades level 9 spells and the last two Cores from cleric trees for access to tier-5 Knight of the Chalice or Sacred Defender to up their melee DPS or tankiness, respectively. It's not something you should do without a specific build goal IMO.