I would love to see an update to potions of wonder. Some funny and entertaining negatives and positives would be awesome. These used to be fun, now they are just a lame aspect of the game.
Some ideas for negatives (what makes them great):
Turn into a frog and hop around useless for 5min
Turn into a kobold and say kobold hate you over and over again
Turn into a beholder and cast an anti magic field around you (and others if close)
Some ideas for positives:
10min temp +4 stats and skills
5min total invulnerability
5min quad damage
10min 50% movement increase