I've been playing DDO a long time. A glance at my join date will tell you that.
I've seen the game go through *many* changes... regular enhancements are on their third itteration. Back when they went to overhaul the original enhancement system (when you only had FOUR enhancemnts total), I cried foul. I cried doom, and was ever so irate because I was loosing Fighter's Dodge II. I lost 2 points of armor class, which back then was kind of a big deal for a tank.
Now, what did I get in return for the two points of AC? A lot of things. Haste boost, more weapon damage, more intimidate, more hit points... but all I could see, initially, was what I lost.
The new epic destiny system will shake things up. The meta will likely, in many ways, be turned on its head. But you know what? DDO will survive.
I'm not telling you to ****. Voice your opinions, offer contructive criticism. The preview is not the be-all-end-all-this-is-how-its-gonna-be. I know that tons of people are threatening to quit... how many will? A drop in the bucket. The rest of us will figure out the new system, and most of us will enjoy it. DDO will survive.