This guide is for Steam on PC.
If someone knows a method for people who do not use Steam, please share.
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1. Go to your Steam “Library” and click “Add a Game” at the bottom left corner,
and then click “Add a Non-Steam Game”.
2. Check the box next to “Dungeons & Dragons Online” where it shows up on the alphabetical list,
and click "Add Selected Programs".
3. Right-click the game in your Library and click “Properties”.
4. In Properties,
a) go to “Change…” and
b) find the “DNDLauncher.exe”,
c) click it so it shows up as “File name” and then click “Open”
d) so that it appears as “Target:”.
5. While you’re still in the Properties menu,
go to “Set Launch Options…” and copy-paste this command:
"<path to DDO>\DNDLauncher.exe" -skiprawdownload -nosplash %command%
If you did everything correctly, your DNDLauncher should now go straight to loading screen when you click “Play” in your Steam Library.
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Credit for this guide goes to Vrakyas.