Rise from your grave! Just wanted to ping this admittedly old thread to give people my personal experience tonight. I have a new computer (Yay!) with Windows 10, and when I installed DDO, I ran into the problem stated in this thread where the game launcher launched, and I was able to log in fine, but when I'd select a world and try to enter the launcher simply disappeared. I tried various things I knew about, including giving the client an exception in my firewall, running as administrator, making sure I had C++ redistributable installed, but to no avail. It wasn't until I ran and installed Microsoft's Direct X End-User Runtime that it began working without issue. FYI: The above link is fine, although it means you need to install the files in your system. A perhaps better link that exists nowadays is this one:
https://www.microsoft.com/en-us/down...ils.aspx?id=35 as it's a web-based installer, and does all the installation work for you.