insofar as it doesn't cause me strife, yes, i do. a moment of "oh, darn," sure. that's about it.
i suppose if there is a difference, it's that fighting champs or facing any other challenge, i have personal control over my own actions and reactions.
but overall, i won't say DDO has never irked me. on the other hand i've been playing on and off since 2006 so obviously all the changes and/or bugs and issues haven't bothered me that much.