Instead of using CR80 wolves with 250k hp, be creative...
In epics a purple named boss (spell caster) will have researched a new epic spell 'curse of opposite alignment).
effect is obvious - character get a curse debuff that switches their alignment.
game effect is dramatic - monks are no longer lawful so lose stance and all monk abilities. same with pally, and chaotic barbs/bards. Most divines are no longer within one step of their deity and lose spell casting. I'm sure there are other effects for other classes but those are the most prominent.
So much for the op monk/pally splash and bards. As a curse, it's not permanent so there will not be evil characters running around (which DDO doesn't allow in character creation).
Just a suggestion and an example of something other than massively inflated hp on everything