With DDO, and NOT with ANY other game I have, have had this issue for a while now. Every time game loads an area it might cause the latest (seems to be the case with few older ones too not sure if some older version still works) AMD display driver to crash, sometimes happens even when not loading an area but usualy it crashes when I switch an area. And no I don't mean crash while loading I mean it loads so I can see the next, and then it freezes and then goes to desktop.
AMD HD7970 latest drivers
Windows 7 64 bit
latest DirectX9 and later
Visual C++ 2005, 2008, 2010, 2012
NetFrame 1.1 and 4.5
Also reinstalled the game once and the smaller files a few times more. Changing display settings to less taxing doesn't matter. Every time also had DX11 mode on, not tried on others, but the game worked fine a year ago, or even during the UD release.
Removed the diag files.
Edit: So far haven't frozen on DX9-mode but it would be a set back, game was working fine with DX11 on before.