On my melees I am just bonkers for healing amp, exceptional fort, dodge, ghostly, blurry, and displacement, anything to allow the character to survive long enough to have a chance to defeat the enemy.
As part of that, everyone regardless of class has at least the 30% healing amp gloves and 20% somewhere else, and if they are not already Unyielding Sentinel then they twist Brace for Impact at the earliest possible moment and keep it forever. Brace for impact is especially critical because in order for Fort to be kept up on EE it has to be at least, what, 155% or so? And the only way to do that currently is Brace for Impact + a 25% item.
On melees, that is a simple twist choice. There are a few other tempting tier one items (Rej. Coccoon, Healing Spring, Unearthly Reactions, Tunnel Vison if you aren't immune to rage) but overall it is just something that has to be done so you do it.
But on casters, I have a heck of a time fitting in either healing amp items or enhancements or exceptional fort, especially twisting Brace for Impact, which is critical to making exceptional fort worth anything. How critical is this really? For you guys with a lot of experience in epics, how have you done either with or without healing amp and/or exceptional fort on your casters?