Short term? Yeah, you might get enfeebled a bit. Your carry limit might annoy you a bit too. I'm leveling an Arty at the moment and I confess that I can be found helpless every now and then.
So what? Carry some lesser restoration potions. Use the deathward goggles from Tangleroot.
Long term? Once you get to the endgame, all it takes is a common +2 Tome, a ship buff, the rage spell, and a +6 Str item fitted on somewhere and you're settled. I have both a Sorc and a FvS with 8 base Str and they never have any issues carrying a full backpack of stuff. Ever.
At this point, even if you (were caught without deathward for some reason and) got hit by some form of energy drain, your UMD constistency with Restoration and Heal Scrolls with should be enough to render it moot anyway. Afterall, its not like you'd be helpless after one enfeeblement (oh no, my total modified str of 18-20 went down to say, 11 or something. Whatever shall I do? /chucks heal scroll; /clickies Tangleroot Goggles; /nags healer for forgetting our deathward).
So unless you've pre-intended to TR, don't waste valuable attribute points on str when you are a caster.
Max your Cha, max you Con, put the remainder in Int. There, you are done.
~TheHolyDarkness Out~