Like a few other masochists I enjoy dual boxing DDO, that is playing two characters at once on two separate instances of DDO.

However as I also suffer from altitis I've been messing around trying to find a good combination of two characters and their classes. My front runners so far are:

Barbarian/Ranger main with Rogue support
Wizard main with Cleric support

What combinations of pure or multiclass characters would work well together?