When set on Defensive they no long will cast remove curse on you or themselves and will not heal you unless manually told to. What they will Do is run half way across the map to melee any monster that is agroed on you. Even if you call them back they will run back. Only way to avoid this is to Set them on passive. Also when cursed now they will drain there mans trying to casts heals that won't land. Basically Cleric and Favored souls hireling now seem to prioritize Melee combat over Everything else. I liked it better when cleric Actuary healed you and Used wands on ememys rather then charging them like barbarians and dying fast.