With so many "bind on equip" items, an inadvertant double-click can ruin a carefully farmed or crafted item.
I propose a "no equip" flag, similar to the locked flag. If an item is marked as "no equip", it cannot be equipped without removing that flag.
Newly crafted/aquired bind on equip items should have this flag set. Acquiring includes anything which puts it on a new character e.g trading, getting it in the mail, crafting it, taking it from the bank. This should probably be a toggleable setting.
Alternatively, give us an "are you sure" dialog when equiping a bind on equip item!