Something to keep in mind there, the alignment infusion is appealing over the damage infusion when the non DR-breaking weapon does no less than the DR value minus the damage infusion amount, than the alternative DR-breaking weapon.
Example:
DR breaker does 60 damage a swing to boss.
Non DR breaker does 50.
Boss DR is 20.
Infusion adds 5 damage per hit.
DR breaker will do 65 optimally, but the non DR breaker will now do 70.
But if the difference between the two is greater, or the DR smaller, it can change. If we change that 60 to higher than 70 then Align Weapon is not the good choice.