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Originally Posted by
TheDjinnFor
As healers, Clerics generally throw bigger heals because they're more likely to choose the Empower Healing feat due to their enhancements (and now the Radiant Servant boost to it). A cleric mass healing a group of >500 hp types probably won't waste a single drop. Good cleric players have no problem solo healing Shrouds if the melees can take the punishment and they pause slightly in between mass heals.
Favored Souls last a lot longer when healing, however. They can keep up a steady stream of Mass cures or spot heals for a long time. Favored Souls might grab Empower Healing but I don't know too many who do instead of something like Maximize or Empower for their BBs. High CHA clerics can mitigate some of the SP loss by DVing other healers.
As melees, Clerics can comfortably splash more levels of fighter, monk, and rogue without missing their high-level spells and because their capstone isn't that great. They can better do 2 Fighter/2 Monk/2 Rogue splashes without much sacrifice.
Favored Souls have much better damage output should they choose to go melee. They have enhancements to improve it and their capstone gives them great durability. Of course, they lose out on their capstone when they splash, so it's a bit of a tradeoff.
For buffing, clerics can grab all the meaningful end-game buffs without any loss, and switch them out between quests depending on the situation. In Epic a Shield of Faith spell can save a tank an item slot, and now that Holy Aura works (supposedly) on groups a +4 resistance for everyone is nice. Last I checked FvS lose anywhere from 3 to 11 spells, depending on what you value as a divine caster and how much you splash. Some FvS will argue you lose nothing, but that's subjective and based on the player.
On the other hand, if FvS know what they need they can take it and be fine. If you're planning on doing one thing and one thing only when you cap (such as running shroud all day) you know exactly what spells you'll need and you'll be okay. On the other hand, if you do a little of everything you could find yourself lacking key spells at raids. If you want to run all the end-game raids and do a lot of solo loot runs while playing Epic you could stretch your FvS.
In terms of Damage spells (i.e. Blade Barrier), FvS are more naturally inclined to it, as they have much more SP to work with and much more durability to survive kiting things around. A cleric can mitigate some benefits if they choose to go with Empower/Maximize instead of Empower Heal, which they may often do. When insta-kills don't work, Clerics can afford to slot CC spells while FvS will more often than not go with insta-kills because they are more practical for a lot of high level play.
In a nutshell, Clerics lose less if they choose to specialize. Favored Souls are better when they specialize, but they lose a lot more versatility. Clerics are naturally more inclined to buffing and healing, while FvS are naturally more inclined to meleeing and DPS. Clerics can CC, buff, DPS (melee and spell), and heal all in one build without losing too much, but FvS generally can't.
If you're new to divines, go cleric; you'll get a mix of everything. Once you know what you like doing you can consider the FvS.
Also: inb4flamewar