I was playing DDO for several hours yesterday with no problem on Windows XP Professional.
After updating DDO today my computer has crashed twice within 2 minutes of logging in with a character.
Not a BSOD crash like I was experiencing on the Windows 7 boot (which appears to be related to an unstable Windows 7 Update) but simply a total freeze.
Graphics Card: Geforce 9600 GT
Memory: 8GB
OS: Windows XP Professional, SP 2
CPU: AMD Phenom II Quad Core
Considering that I was running DDO just fine right before this patch (on Windows XP), I don't believe the problem is on my end.