Originally Posted by
Zenako
If you have not run the Sharn Syndicate yet, some of the End Reward Weapons are very nice and useful for situation like this. The Heavy Mace is an excellent all around beater, since the extra "elemental damage" is FORCE, which pretty much nothing is resistent or immune to. So a d8+1 base damage +d6 FORCE damage is useful against a huge range of foes.
As a heads up, when something like a SKeleton has Damage Reduction against Pierce, it is usually something on the order of DR5 so unless your damage was over 5 total points, you would get a 0.
Also the AC of some mobs is enough that you will likely be getting a few glancing blows which only look at base weapon damage and that will be even more likely to end up at a net of 0.