This is an OOOOLD fix for getting Data Centers bug from 2007. Still works for me though.
Step 1: Find your D&D Online install directory. Typically, this is C: -> Program Files -> Turbine - DDO
Step 2: Create a .txt file. (Notepad file) Name the .txt file "dndlauncher.exe.config" minus the quotation marks.
Step 3: Paste the following into Notepad file.
<?xml version="1.0" encoding="utf-8"?>
<configuration>
<system.windows.forms jitDebugging="true"/>
<startup>
<requiredRuntime version="V1.1.4322" safemode="true"/>
<supportedRuntime version="V1.1.4322" />
</startup>
<appSettings>
<add key="Launcher.DataCenterService.GLS" value="http://gls.ddo.com/GLS.DataCenterServer/Service.asmx"/>
<add key="DataCenter.GameName" value="DDO"/>
<add key="DataCenter.DefaultCenter" value="DDO"/>
<add key="Product.DocumentFolder" value="Dungeons and Dragons Online"/>
<add key="Launcher.DocumentFolder" value="Launcher"/>
</appSettings>
</configuration>
Step 4: Save the Notepad file in the Dungeons and Dragons Online.
Step 5: Log on!