I followed much of Melkor's advice in his build thread here:
http://forums.ddo.com/showthread.php?t=211596
I skipped the THF feats completely, as he did, and can't say I ever missed them. To be fair, when I built mine THF was much less worthwhile than it is now, but I still can't see the added damage being worth the metamagics I'd have to give up for it. And, as you say, I move around a lot. DDO combat forces a lot of movement, with the major exception of raid boss fights, so the advantage of the THF line is situational.
I have Empower Healing and Maximize both. No Empower. I consider Maximize a must, and when it came down to choosing between EH and Empower, EH costs less than Empower for the Cure spells and works on 2 spells I cast all the time, Heal and Mass Heal, whereas Empower only affects 1 spell I usually cast, Blade Barrier. If you dump WIS and cast no offensive spells, or only BB, then Empower just doesn't offer enough for my money.
Extend is a very handy feat. While leveling it was invaluable to prevent having to recast buffs. At cap I don't need it anymore for my 20 min. buffs but I still find a lot of use for it on Divine Favor, Divine Power, Recitation and Holy Aura. I could do without it if I had to but I honestly don't know which feat would offer me more than it does.
My feat breakdown:
1) Adamantine Body -> swapped to Empower Healing later
3) Toughness
6) Extend
9) Quicken
12) IC: Slashing
15) Maximize
18) Power Attack
On the subject of stats, I started with an 18 STR but when I LR'd I dropped that to a 16 and used the extra points on a 12 INT and a little DEX. I like having Concentration, Balance and Jump as skills and that works better for me than the extra point of hit and damage, but of course YMMV.
Hope that helps some.